Clindamycin Phosphate 1.2% + Benzoyl Peroxide 5% Gel (45g)
From: $45.00/month
A powerful dual-action acne treatment that combines an antibiotic (clindamycin) with benzoyl peroxide to fight breakouts fast, unclog pores, reduce inflammation, and prevent new acne from forming.
⚠️ Safety Information
⚠️ Serious Warnings / Precautions
- Both ingredients may cause dryness, irritation, redness, and peeling—especially during the first 2–4 weeks.
- Avoid applying to sunburned, broken, or severely irritated skin.
- May increase sensitivity to sunlight; daily SPF 30+ is strongly recommended.
- Rarely, clindamycin can cause severe diarrhea or colitis, even weeks after stopping. Contact a clinician immediately if severe or persistent diarrhea occurs.
- Stop use and seek care if you develop severe redness, crusting, blistering, or swelling.
- Benzoyl peroxide can bleach fabrics (towels, clothing, bedding, hair).
🚫 Who Should NOT Use This Medication
- Anyone allergic to clindamycin, benzoyl peroxide, lincomycin, or any formulation ingredients.
- People with a history of severe diarrhea, C. diff infection, or antibiotic-associated colitis.
- Do not apply on areas with eczema, broken skin, or severe sunburn.
- Pregnancy or breastfeeding: only use if approved by your clinician.
💊 How to Use
- Apply a thin layer to clean, fully dry skin once daily (or as directed).
- Start every other night if you have sensitive skin, then increase as tolerated.
- Avoid eye area, mouth corners, and nostrils.
- Use a gentle moisturizer 5–10 minutes after applying if dryness occurs.
- Always use sunscreen during the day.
🧴 Common Side Effects
- Dryness, peeling, flaking
- Mild stinging or burning
- Redness or irritation
- Bleaching of clothing, bedding, or hair
⚠️ Serious Side Effects (Seek Care)
- Severe diarrhea, abdominal cramping, or bloody stools
- Severe swelling, blistering, or crusting of treated areas
- Allergic reaction: rash, hives, difficulty breathing (urgent care)
📦 Storage & Handling
- Store at room temperature, away from heat and direct light.
- Keep tightly closed to prevent oxidation.
- Keep out of reach of children.
Disclaimer: This summary is for informational purposes only and not a substitute for professional medical advice.
❓ Frequently Asked Questions
⏱️ How long does this medication take to work?
Most users begin to see reduced inflammation and fewer active pimples within 4–8 weeks, with optimal results around 12 weeks of consistent use.
🔥 Why is my skin getting red, dry, or peeling?
Dryness and irritation are common during the first few weeks due to benzoyl peroxide. This usually improves as your skin adjusts. Use moisturizer and follow your clinician’s instructions for gradual introduction.
📉 Will my acne get worse before it gets better?
Some users experience “purging,” where clogged pores surface before clearing improves. This typically resolves within the first 2–6 weeks.
🌞 Do I need sunscreen while using this?
Yes. Benzoyl peroxide can increase sun sensitivity. Daily broad-spectrum SPF 30+ is strongly recommended.
💧 Can I use moisturizer with this medication?
Yes — moisturizers are encouraged! They help reduce dryness, peeling, and irritation. Use non-comedogenic products.
🧴 Can I use this with tretinoin or retinol?
Yes, but introduce slowly. Many clinicians recommend using BPO/clindamycin in the morning and tretinoin at night to reduce irritation. Follow your provider’s instructions.
🧼 Should I apply this before or after moisturizer?
Apply to clean, dry skin. Moisturizer can be applied after. If you have sensitive skin, you may apply moisturizer first (“buffering”) to reduce irritation.
🛏️ Will this bleach my towels, sheets, or clothes?
Yes. Benzoyl peroxide commonly bleaches fabrics. Use white pillowcases, towels, and clothing when possible.
💄 Can I wear makeup over this?
Yes. Allow the medication to fully dry before applying makeup. Choose non-comedogenic products.
🪒 Can I shave the areas where I apply it?
Yes, but shaving may increase irritation. Consider shaving at a different time of day than application.
🧍 Can I use this on my chest or back acne?
Yes. This combination is commonly used for face, chest, and back acne. Apply a thin layer to clean, dry skin.
🤰 Is it safe during pregnancy or breastfeeding?
Use only if approved by your clinician. Benzoyl peroxide is often considered low risk, but clindamycin should be evaluated on a case-by-case basis.
🛑 Can I stop using it once my acne clears?
You may reduce frequency, but acne can return if treatment is stopped completely. Many users continue with a maintenance routine.
😣 I have sensitive skin. Can I still use this?
Yes — but start slowly (every other night or 2–3 nights weekly) and moisturize. Your clinician can help tailor a routine.
🦠 Does this cause antibiotic resistance?
Benzoyl peroxide significantly reduces the risk of bacterial resistance when used with clindamycin — one reason this combination is widely preferred.
⚡ Will this help cystic or deep painful acne?
It may help reduce surface inflammation, but cystic acne often needs stronger medications like oral antibiotics, hormonal therapy, or isotretinoin. Your clinician can advise.
🌑 Will this help with acne dark spots (PIH)?
It prevents new breakouts (which reduces new dark marks), but PIH often needs additional agents like tretinoin, azelaic acid, or brightening creams.
🧽 What kind of cleanser should I use with this?
Use a gentle, non-foaming, non-exfoliating cleanser. Avoid scrubs, acids, and harsh cleansers while adjusting.
📦 How should I store the medication?
Store at room temperature away from heat and direct light. Keep tube tightly closed to prevent oxidation.
🌅 Should I use it in the morning or at night?
Most clinicians recommend morning use because benzoyl peroxide pairs well with nighttime retinoids. Follow your specific instructions.
Additional information
| Billing Cycle | Monthly, Quarterly, Semi-annual, Annual |
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